Brown ground beef and ground sausage in a large skillet; drain excess grease if needed.
Add diced Velveeta, garlic powder, Worcestershire sauce and oregano (optional), and cook on low, stirring until cheese is melted.
Arrange cocktail bread on a large sheet pan.
Top each slice with 1 tablespoon of meat mixture.
Bake in a preheated 400 degree oven for 10 minutes or until golden brown and hot.
See notes for freezing instructions.